通过直接重新编程制造心肌诱导心肌样细胞（iCM细胞：induced cardiomyocytes）

可以配备温度及CO2控制培养室

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拍摄要点

在小鼠胚胎纤维芽细胞中导入3种心肌特异性转录因子并培养一周，就能不借助iPS细胞，直接制造心肌样细胞（iCM细胞：induced cardiomyocytes）。继续培养三周，就能观察到跳动的iCM细胞。

拍摄条件

• 倍率：×20相位差
• 帧率：30 fps

供图

筑波大学医学医疗系循环器内科
家田真树教授
庆应义塾大学医学部循环器内科
山川裕之助教